Publications listed represent all or part of the research that was carried out using PNCC resources.

Check out PNCC Usage Disclaimers for information regarding acknowledgements, data sharing & publications.

Gabe Lander has provided an excellent guide for cryo-EM data validation typically expected during peer review of manuscripts.

 

PNCC Publications

As of January 30th, 2024, PNCC Users have published 162 peer reviewed publications with an average impact factor of 21 and a median impact factor of 16. During this same timeframe, over 500 PDB depositions and over 600 EMDB depositions have resulted from use of PNCC.

 

2019

  1. "Architecture of the chromatin remodeler RSC and insights into its nucleosome engagement"    eLife    DOI: 10.7554/eLife.54449

 

2020

  1. "The Cryo-EM structure of AAV2 Rep68 in complex with ssDNA reveals a malleable AAA+ machine that can switch between oligomeric states"    Nucleic Acids Research    DOI: 10.1093/nar/gkaa1133
  2. "Mechanism and inhibition of Streptococcus pneumoniae IgA1 protease"    Nature Communications    DOI: 10.1038/s41467-020-19887-3
  3. "Structure of bacterial phospholipid transporter MlaFEDB with substrate bound"    eLife    DOI: 10.7554/eLife.62518
  4. "Light-coupled cryo-plunger for time-resolved cryo-EM"    Journal of Structural Biology    DOI: 10.1016/j.jsb.2020.107624
  5. "Shared structural mechanisms of general anaesthetics and benzodiazepines"    Nature    DOI: 10.1038/s41586-020-2654-5
  6. "Connexin-46/50 in a dynamic lipid environment resolved by CryoEM at 1.9 ≈"    Nature Communications    DOI: 10.1038/s41467-020-18120-5
  7. "Structural basis of transcription-translation coupling"    Science    DOI: 10.1126/science.abb5317
  8. "Molecular principles of assembly, activation, and inhibition in epithelial sodium channel"    eLife    DOI: 10.7554/eLife.59038
  9. "Subdomain cryo-EM structure of nodaviral replication protein A crown complex provides mechanistic insights into RNA genome replication"    Proceedings of the National Academy of Sciences    DOI: 10.1073/pnas.2006165117
  10. "The His-Gly motif of acid-sensing ion channels resides in a reentrant ëloopí implicated in gating and ion selectivity"    eLife    DOI: 10.7554/eLife.56527
  11. "The Structure of an AAV5-AAVR Complex at 2.5 ≈ Resolution: Implications for Cellular Entry and Immune Neutralization of AAV Gene Therapy Vectors"    Viruses    DOI: 10.3390/v12111326
  12. "Structural basis for the reaction cycle of DASS dicarboxylate transporters"    eLife    DOI: 10.7554/eLife.61350
  13. "Chemical and structural investigation of the paroxetine-human serotonin transporter complex"    eLife    DOI: 10.7554/eLife.56427
  14. "Deconvoluting Lipid Nanoparticle Structure for Messenger RNA Delivery"    Nano Letters    DOI: 10.1021/acs.nanolett.0c01386
  15. "Structure of the Native Muscle-type Nicotinic Receptor and Inhibition by Snake Venom Toxins"    Neuron    DOI: 10.1016/j.neuron.2020.03.012
  16. "Structures of Three Actinobacteriophage Capsids: Roles of Symmetry and Accessory Proteins"    Viruses    DOI: 10.3390/v12030294
  17. "Structure of the human cationñchloride cotransporter NKCC1 determined by single-particle electron cryo-microscopy"    Nature Communications    DOI: 10.1038/s41467-020-14790-3
  18. "Cryo-EM structures provide insight into how E. coli F1Fo ATP synthase accommodates symmetry mismatch"    Nature Communications    DOI: 10.1038/s41467-020-16387-2

 

2021

  1. "Mechanism of filament formation in UPA-promoted CARD8 and NLRP1 inflammasomes"    Nature Communications    DOI: 10.1038/s41467-020-20320-y
  2. "Structures of monomeric and dimeric PRC2:EZH1 reveal flexible modules involved in chromatin compaction"    Nature Communications    DOI: 10.1038/s41467-020-20775-z
  3. "Structural analysis of RIG-I-like receptors reveals ancient rules of engagement between diverse RNA helicases and TRIM ubiquitin ligases"    Molecular Cell    DOI: 10.1016/j.molcel.2020.11.047
  4. "Structural Basis for Virulence Activation of Francisella tularensis"    Molecular Cell    DOI: 10.1016/j.molcel.2020.10.035
  5. "A Non-covalent Ligand Reveals Biased Agonism of the TRPA1 Ion Channel"    Neuron    DOI: 10.1016/j.neuron.2020.10.014
  6. "Structure and function of the calcium‐selective TRP channel TRPV6"    The Journal of Physiology    DOI: 10.1113/JP279024
  7. "NLRP3 cages revealed by full-length mouse NLRP3 structure control pathway activation"    Cell    DOI: 10.1016/j.cell.2021.11.011
  8. "Illumination of serotonin transporter mechanism and role of the allosteric site"    Science Advances    DOI: 10.1126/sciadv.abl3857
  9. "A viral RNA hijacks host machinery using dynamic conformational changes of a tRNA-like structure"    Science    DOI: 10.1126/science.abe8526
  10. "Vascular K <sub>ATP</sub> channel structural dynamics reveal regulatory mechanism by Mg-nucleotides"    Proceedings of the National Academy of Sciences    DOI: 10.1073/pnas.2109441118
  11. "Purification and cryo-EM structure determination of Arabidopsis thaliana GLR3.4"    STAR Protocols    DOI: 10.1016/j.xpro.2021.100855
  12. "Architecture and assembly mechanism of native glycine receptors"    Nature    DOI: 10.1038/s41586-021-04022-z
  13. "Tunable Heteroassembly of a Plant Pseudoenzyme-Enzyme Complex"    ACS Chemical Biology    DOI: 10.1021/acschembio.1c00475
  14. "AAA+ ATPase p97/VCP mutants and inhibitor binding disrupt inter-domain coupling and subsequent allosteric activation"    Journal of Biological Chemistry    DOI: 10.1016/j.jbc.2021.101187
  15. "Structural mechanisms of TRPV6 inhibition by ruthenium red and econazole"    Nature Communications    DOI: 10.1038/s41467-021-26608-x
  16. "Cryo-EM structures of the ABCA4 importer reveal mechanisms underlying substrate binding and Stargardt disease"    Nature Communications    DOI: 10.1038/s41467-021-26161-7
  17. "Structural basis of chromatin regulation by histone variant H2A.Z"    Nucleic Acids Research    DOI: 10.1093/nar/gkab907
  18. "Structural mechanism of TRPV3 channel inhibition by the plant&#8208;derived coumarin osthole"    EMBO reports    DOI: 10.15252/embr.202153233
  19. "Structure of the phosphoinositide 3-kinase (PI3K) p110&#947;-p101 complex reveals molecular mechanism of GPCR activation"    Science Advances    DOI: 10.1126/sciadv.abj4282
  20. "The antidepressant drug vilazodone is an allosteric inhibitor of the serotonin transporter"    Nature Communications    DOI: 10.1038/s41467-021-25363-3
  21. "Structural and mechanistic basis for protein glutamylation by the kinase fold"    Molecular Cell    DOI: 10.1016/j.molcel.2021.08.007
  22. "Molecular mechanism of prestin electromotive signal amplification"    Cell    DOI: 10.1016/j.cell.2021.07.034
  23. "Structures of the mycobacterial membrane protein MmpL3 reveal its mechanism of lipid transport"    PLOS Biology    DOI: 10.1371/journal.pbio.3001370
  24. "Structural basis for potassium transport in prokaryotes by KdpFABC"    Proceedings of the National Academy of Sciences    DOI: 10.1073/pnas.2105195118
  25. "Accurate prediction of protein structures and interactions using a three-track neural network"    Science    DOI: 10.1126/science.abj8754
  26. "Zinc binding alters the conformational dynamics and drives the transport cycle of the cation diffusion facilitator YiiP"    Journal of General Physiology    DOI: 10.1085/jgp.202112873
  27. "Heat-dependent opening of TRPV1 in the presence of capsaicin"    Nature Structural & Molecular Biology    DOI: 10.1038/s41594-021-00616-3
  28. "Structural mechanism of heat-induced opening of a temperature-sensitive TRP channel"    Nature Structural & Molecular Biology    DOI: 10.1038/s41594-021-00615-4
  29. "Structural basis for CSPG4 as a receptor for TcdB and a therapeutic target in Clostridioides difficile infection"    Nature Communications    DOI: 10.1038/s41467-021-23878-3
  30. "Structural insight on assembly-line catalysis in terpene biosynthesis"    Nature Communications    DOI: 10.1038/s41467-021-23589-9
  31. "HDX-MS-optimized approach to characterize nanobodies as tools for biochemical and structural studies of class IB phosphoinositide 3-kinases"    Structure    DOI: 10.1016/j.str.2021.07.002
  32. "Mechanisms of BRCA1ñBARD1 nucleosome recognition and ubiquitylation"    Nature    DOI: 10.1038/s41586-021-03716-8
  33. "Structure of the Arabidopsis thaliana glutamate receptor-like channel GLR3.4"    Molecular Cell    DOI: 10.1016/j.molcel.2021.05.025
  34. "Dipeptidyl peptidase 9 sets a threshold for CARD8 inflammasome formation by sequestering its active C-terminal fragment"    Immunity    DOI: 10.1016/j.immuni.2021.04.024
  35. "Extracellular cap domain is an essential component of the TRPV1 gating mechanism"    Nature Communications    DOI: 10.1038/s41467-021-22507-3
  36. "Coordination of phage genome degradation versus host genome protection by a bifunctional restriction-modification enzyme visualized by CryoEM"    Structure    DOI: 10.1016/j.str.2021.03.012
  37. "Cryo-EM structures of HIV-1 trimer bound to CD4-mimetics BNM-III-170 and M48U1 adopt a CD4-bound open conformation"    Nature Communications    DOI: 10.1038/s41467-021-21816-x
  38. "DPP9 sequesters the C terminus of NLRP1 to repress inflammasome activation"    Nature    DOI: 10.1038/s41586-021-03350-4
  39. "Hippocampal AMPA receptor assemblies and mechanism of allosteric inhibition"    Nature    DOI: 10.1038/s41586-021-03540-0
  40. "Structural basis of long-range to short-range synaptic transition in NHEJ"    Nature    DOI: 10.1038/s41586-021-03458-7
  41. "Cryo-EM structure of a thermostable bacterial nanocompartment"    IUCrJ    DOI: 10.1107/S2052252521001949
  42. "Production and purification of ATP-sensitive potassium channel particles for cryo-electron microscopy"    Methods in Enzymology    DOI: 10.1016/bs.mie.2021.02.008
  43. "Structure and gating mechanism of the &#945;7 nicotinic acetylcholine receptor"    Cell    DOI: 10.1016/j.cell.2021.02.049
  44. "TRPV3 expression and purification for structure determination by Cryo-EM"    Methods in Enzymology    DOI: 10.1016/bs.mie.2021.02.006
  45. "Structure of the human Mediator-bound transcription preinitiation complex"    Science    DOI: 10.1126/science.abg3074
  46. "CorRelator: Interactive software for real-time high precision cryo-correlative light and electron microscopy"    Journal of Structural Biology    DOI: 10.1016/j.jsb.2021.107709
  47. "Structure and inhibition mechanism of the human citrate transporter NaCT"    Nature    DOI: 10.1038/s41586-021-03230-x
  48. "Illuminating endosomal escape of polymorphic lipid nanoparticles that boost mRNA delivery"    Biomaterials Science    DOI: 10.1039/D0BM01947J
  49. "Molecular structures and conformations of protocadherin-15 and its complexes on stereocilia elucidated by cryo-electron tomography"    eLife    DOI: 10.7554/eLife.74512
  50. "Cryo-EM reveals unique structural features of the FhuCDB Escherichia coli ferrichrome importer"    Communications Biology    DOI: 10.1038/s42003-021-02916-2

 

2022

  1. "Sequence-specific remodeling of a topologically complex RNP substrate by Spb4"    Nature Structural & Molecular Biology    DOI: 10.1038/s41594-022-00874-9
  2. "A substrate-induced gating mechanism is conserved among Gram-positive IgA1 metalloproteases"    Communications Biology    DOI: 10.1038/s42003-022-04173-3
  3. "Transient PrenyltransferaseñCyclase Association in Fusicoccadiene Synthase, an Assembly-Line Terpene Synthase"    Biochemistry    DOI: 10.1021/acs.biochem.2c00509
  4. "Activation mechanism of the mouse cold-sensing TRPM8 channel by cooling agonist and PIP <sub>2</sub>"    Science    DOI: 10.1126/science.add1268
  5. "Structural principles of B cell antigen receptor assembly"    Nature    DOI: 10.1038/s41586-022-05412-7
  6. "Molecular asymmetry of a photosynthetic supercomplex from green sulfur bacteria"    Nature Communications    DOI: 10.1038/s41467-022-33505-4
  7. "Structural basis for APE1 processing DNA damage in the nucleosome"    Nature Communications    DOI: 10.1038/s41467-022-33057-7
  8. "Methotrexate recognition by the human reduced folate carrier SLC19A1"    Nature    DOI: 10.1038/s41586-022-05168-0
  9. "Mechanism of mixed-linkage glucan biosynthesis by barley cellulose synthaseñlike CslF6 (1,3;1,4)-&#946;-glucan synthase"    Science Advances    DOI: 10.1126/sciadv.add1596
  10. "Structures of the TMC-1 complex illuminate mechanosensory transduction"    Nature    DOI: 10.1038/s41586-022-05314-8
  11. "Cryo-EM Structure and Functional Studies of EBNA1 Binding to the Family of Repeats and Dyad Symmetry Elements of Epstein-Barr Virus <i>oriP</i>"    Journal of Virology    DOI: 10.1128/jvi.00949-22
  12. "Cryo-EM reveals an entangled kinetic trap in the folding of a catalytic RNA"    Science Advances    DOI: 10.1126/sciadv.abq4144
  13. "Structural and dynamic mechanisms of GABAA receptor modulators with opposing activities"    Nature Communications    DOI: 10.1038/s41467-022-32212-4
  14. "Conformational landscape of the yeast SAGA complex as revealed by cryo-EM"    Scientific Reports    DOI: 10.1038/s41598-022-16391-0
  15. "Structure of the rabies virus glycoprotein trimer bound to a prefusion-specific neutralizing antibody"    Science Advances    DOI: 10.1126/sciadv.abp9151
  16. "Superimmunity by pan-sarbecovirus nanobodies"    Cell Reports    DOI: 10.1016/j.celrep.2022.111004
  17. "Structural mechanism of TRPV3 channel inhibition by the anesthetic dyclonine"    Nature Communications    DOI: 10.1038/s41467-022-30537-8
  18. "Structural basis for inhibition of the Cation-chloride cotransporter NKCC1 by the diuretic drug bumetanide"    Nature Communications    DOI: 10.1038/s41467-022-30407-3
  19. "The promise of cryo-EM to explore RNA structural dynamics"    Journal of Molecular Biology    DOI: 10.1016/j.jmb.2022.167802
  20. "Visualization of conformational changes and membrane remodeling leading to genome delivery by viral class-II fusion machinery"    Nature Communications    DOI: 10.1038/s41467-022-32431-9
  21. "Coupling to short linear motifs creates versatile PME-1 activities in PP2A holoenzyme demethylation and inhibition"    eLife    DOI: 10.7554/eLife.79736
  22. "Structurally derived universal mechanism for the catalytic cycle of the tail-anchored targeting factor Get3"    Nature Structural & Molecular Biology    DOI: 10.1038/s41594-022-00798-4
  23. "Structural basis for inhibition and regulation of a chitin synthase from Candida albicans"    Nature Structural & Molecular Biology    DOI: 10.1038/s41594-022-00791-x
  24. "Structure of the human cation-chloride cotransport KCC1 in an outward-open state"    Proceedings of the National Academy of Sciences    DOI: 10.1073/pnas.2109083119
  25. "Architecture of the linker-scaffold in the nuclear pore"    Science    DOI: 10.1126/science.abm9798
  26. "Vanilloid-dependent TRPV1 opening trajectory from cryoEM ensemble analysis"    Nature Communications    DOI: 10.1038/s41467-022-30602-2
  27. "Ligand-Binding Sites in Vanilloid-Subtype TRP Channels"    Frontiers in Pharmacology    DOI: 10.3389/fphar.2022.900623
  28. "Computational design of mechanically coupled axle-rotor protein assemblies"    Science    DOI: 10.1126/science.abm1183
  29. "Cryo-EM structure of the prothrombin-prothrombinase complex"    Blood    DOI: 10.1182/blood.2022015807
  30. "Structural basis for inhibition of the drug efflux pump NorA from Staphylococcus aureus"    Nature Chemical Biology    DOI: 10.1038/s41589-022-00994-9
  31. "Structural mechanism of muscle nicotinic receptor desensitization and block by curare"    Nature Structural & Molecular Biology    DOI: 10.1038/s41594-022-00737-3
  32. "The structural basis for regulation of the glutathione transporter Ycf1 by regulatory domain phosphorylation"    Nature Communications    DOI: 10.1038/s41467-022-28811-w
  33. "Development of an atmospheric plasma jet device for versatile treatment of electron microscope sample grids"    Journal of Biological Chemistry    DOI: 10.1016/j.jbc.2022.101793
  34. "Gating choreography and mechanism of the human proton-activated chloride channel ASOR"    Science Advances    DOI: 10.1126/sciadv.abm3942
  35. "Asymmetric drug binding in an ATP-loaded inward-facing state of an ABC transporter"    Nature Chemical Biology    DOI: 10.1038/s41589-021-00936-x
  36. "Active conformation of the p97-p47 unfoldase complex"    Nature Communications    DOI: 10.1038/s41467-022-30318-3
  37. "Recovery of particulate methane monooxygenase structure and activity in a lipid bilayer"    Science    DOI: 10.1126/science.abm3282
  38. "Structural mechanism of allosteric activation of TRPML1 by PI(3,5)P <sub>2</sub> and rapamycin"    Proceedings of the National Academy of Sciences    DOI: 10.1073/pnas.2120404119
  39. "An Analysis of the Novel Fluorocycline TP-6076 Bound to Both the Ribosome and Multidrug Efflux Pump AdeJ from Acinetobacter baumannii"    mBio    DOI: 10.1128/mbio.03732-21
  40. "Structural visualization of de novo transcription initiation by Saccharomyces cerevisiae RNA polymerase II"    Molecular Cell    DOI: 10.1016/j.molcel.2021.12.020

 

2023

  1. "Changes within the central stalk of E. coli F1Fo ATP synthase observed after addition of ATP"    Communications Biology    DOI: 10.1038/s42003-023-04414-z
  2. "Structural basis of broad-spectrum &#946;-lactam resistance in Staphylococcus aureus"    Nature    DOI: 10.1038/s41586-022-05583-3
  3. "Mechanism of NAIPóNLRC4 inflammasome activation revealed by cryo-EM structure of unliganded NAIP5"    Nature Structural & Molecular Biology    DOI: 10.1038/s41594-022-00889-2
  4. "Energy coupling and stoichiometry of Zn2+/H+ antiport by the prokaryotic cation diffusion facilitator YiiP"    eLife    DOI: 10.7554/eLife.87167.3
  5. "Structural Mechanisms for VMAT2 inhibition by tetrabenazine"        DOI:
  6. "Product analogue binding identifies the copper active site of particulate methane monooxygenase"    Nature Catalysis    DOI: 10.1038/s41929-023-01051-x
  7. "Molecular pharmacology of the onco-TRP channel TRPV6"    Channels    DOI: 10.1080/19336950.2023.2266669
  8. "Structural basis of promiscuous substrate transport by Organic Cation Transporter 1"    Nature Communications    DOI: 10.1038/s41467-023-42086-9
  9. "Pentameric TRPV3: An artifact or a clue to channel function?"    Cell Calcium    DOI: 10.1016/j.ceca.2023.102812
  10. "Cryo-EM structures reveal native GABAA receptor assemblies and pharmacology"    Nature    DOI: 10.1038/s41586-023-06556-w
  11. "Modulation of GluA2ñ&#947;5 synaptic complex desensitization, polyamine block and antiepileptic perampanel inhibition by auxiliary subunit cornichon-2"    Nature Structural & Molecular Biology    DOI: 10.1038/s41594-023-01080-x
  12. "Structural insights into opposing actions of neurosteroids on GABAA receptors"    Nature Communications    DOI: 10.1038/s41467-023-40800-1
  13. "Structural basis of TFIIIC-dependent RNA polymerase III transcription initiation"    Molecular Cell    DOI: 10.1016/j.molcel.2023.06.015
  14. "Structure of human TRPV4 in complex with GTPase RhoA"    Nature Communications    DOI: 10.1038/s41467-023-39346-z
  15. "TRPV4-Rho GTPase complex structures reveal mechanisms of gating and disease"    Nature Communications    DOI: 10.1038/s41467-023-39345-0
  16. "Structural interplay of anesthetics and paralytics on muscle nicotinic receptors"    Nature Communications    DOI: 10.1038/s41467-023-38827-5
  17. "Cryo-EM visualization of DNA-PKcs structural intermediates in NHEJ"    Science Advances    DOI: 10.1126/sciadv.adg2838
  18. "A generalizable scaffold-based approach for structure determination of RNAs by cryo-EM"    Nucleic Acids Research    DOI: 10.1093/nar/gkad784
  19. "Molecular pathway and structural mechanism of human oncochannel TRPV6 inhibition by the phytocannabinoid tetrahydrocannabivarin"    Nature Communications    DOI: 10.1038/s41467-023-40362-2
  20. "Structure of an endogenous mycobacterial MCE lipid transporter"    Nature    DOI: 10.1038/s41586-023-06366-0
  21. "Mechanism of RanGTP priming H2A-H2B release from Kap114 in an atypical RanGTPïKap114ïH2A-H2B complex"    Proceedings of the National Academy of Sciences    DOI: 10.1073/pnas.2301199120
  22. "Structures and membrane interactions of native serotonin transporter in complexes with psychostimulants"    Proceedings of the National Academy of Sciences    DOI: 10.1073/pnas.2304602120
  23. "Virion glycosylation influences mycobacteriophage immune recognition"    Cell Host & Microbe    DOI: 10.1016/j.chom.2023.05.028
  24. "30S subunit recognition and G1405 modification by the aminoglycoside-resistance 16S ribosomal RNA methyltransferase RmtC"    Proceedings of the National Academy of Sciences    DOI: 10.1073/pnas.2304128120
  25. "Cryo-EM structure of the Saccharomyces cerevisiae Rpd3L histone deacetylase complex"    Nature Communications    DOI: 10.1038/s41467-023-38687-z
  26. "Allosteric activation or inhibition of PI3K&#947; mediated through conformational changes in the p110&#947; helical domain"    eLife    DOI: 10.7554/eLife.88058
  27. "Structure of coagulation factor VIII bound to a patient-derived anti-C1 domain antibody inhibitor"    Blood Journal    DOI: 10.1182/blood.2023020181
  28. "Human TRPV1 structure and inhibition by the analgesic SB-366791"    Nature Communications    DOI: 10.1038/s41467-023-38162-9
  29. "Cryo-EM structure of the human Sirtuin 6-nucleosome complex"    Science Advances    DOI: 10.1126/sciadv.adf7586
  30. "Batch Production of High-Quality Graphene Grids for Cryo-EM: Cryo-EM Structure of <i>Methylococcus capsulatus</i> Soluble Methane Monooxygenase Hydroxylase"    ACS Nano    DOI: 10.1021/acsnano.3c00463
  31. "Cryo-EM structure of amyloid fibril formed by &#945;-synuclein hereditary A53E mutation reveals a distinct protofilament interface"    Journal of Biological Chemistry    DOI: 10.1016/j.jbc.2023.104566
  32. "rRNA methylation by Spb1 regulates the GTPase activity of Nog2 during 60S ribosomal subunit assembly"    Nature Communications    DOI: 10.1038/s41467-023-36867-5
  33. "Positive and negative allosteric modulation of GluK2 kainate receptors by BPAM344 and antiepileptic perampanel"    Cell Reports    DOI: 10.1016/j.celrep.2023.112124
  34. "Nodavirus RNA replication crown architecture reveals proto-crown precursor and viral protein A conformational switching"    Proceedings of the National Academy of Sciences    DOI: 10.1073/pnas.2217412120
  35. "Mechanism of Ca2+ transport by ferroportin"    eLife    DOI: 10.7554/eLife.82947
  36. "Structural basis of ferroportin inhibition by minihepcidin PR73"    PLOS Biology    DOI: 10.1371/journal.pbio.3001936
  37. "Structural mechanism of human oncochannel TRPV6 inhibition by the natural phytoestrogen genistein"    Nature Communications    DOI: 10.1038/s41467-023-38352-5
  38. "Structural mechanisms of TRPM7 activation and inhibition"    Nature Communications    DOI: 10.1038/s41467-023-38362-3
  39. "Structural basis of sensory receptor evolution in octopus"    Nature    DOI: 10.1038/s41586-023-05822-1
  40. "Sensory specializations drive octopus and squid behaviour"    Nature    DOI: 10.1038/s41586-023-05808-z
  41. "Basic helix-loop-helix pioneer factors interact with the histone octamer to invade nucleosomes and generate nucleosome-depleted regions"    Molecular Cell    DOI: 10.1016/j.molcel.2023.03.006
  42. "The molecular mechanism of sialic acid transport mediated by Sialin"    Science Advances    DOI: 10.1126/sciadv.ade8346
  43. "Cryo-EM structure of adeno-associated virus 4 at 2.2 ≈ resolution"    Acta Crystallographica Section D Structural Biology    DOI: 10.1107/S2059798322012190
  44. "Cryo-EM reveals the molecular basis of laminin polymerization and LN-lamininopathies"    Nature Communications    DOI: 10.1038/s41467-023-36077-z
  45. "Unique interface and dynamics of the complex of HSP90 with a specialized cochaperone AIPL1"    Structure    DOI: 10.1016/j.str.2022.12.014
  46. "A structural dendrogram of the actinobacteriophage major capsid proteins provides important structural insights into the evolution of capsid stability"    Structure    DOI: 10.1016/j.str.2022.12.012
  47. "Inhibition of the proton-activated chloride channel PAC by PIP2"    eLife    DOI: 10.7554/eLife.83935
  48. "Molecular Architecture of Salmonella Typhimurium Virus P22 Genome Ejection Machinery"    Journal of Molecular Biology    DOI: 10.1016/j.jmb.2023.168365

 

2024

  1. "Mechanisms of RNF168 nucleosome recognition and ubiquitylation"    Molecular Cell    DOI: 10.1016/j.molcel.2023.12.036
  2. "Structural polymorphism of amyloid fibrils in ATTR amyloidosis revealed by cryo-electron microscopy"    Nature Communications    DOI: 10.1038/s41467-024-44820-3
  3. "Overcoming resolution attenuation during tilted cryo-EM data collection"    Nature Communications    DOI: 10.1038/s41467-023-44555-7
  4. "B56 long-disordered arms form a dynamic PP2A regulation interface coupled with global allostery and Jordanís syndrome mutations"    Proceedings of the National Academy of Sciences    DOI: 10.1073/pnas.2310727120
  5. "Cryo-EM structures of PP2A:B55-FAM122A and PP2A:B55-ARPP19"    Nature    DOI: 10.1038/s41586-023-06870-3
  6. "Structural basis of Gabija anti-phage defence and viral immune evasion"    Nature    DOI: 10.1038/s41586-023-06855-2