The acid-sensing ion channel (ASIC) ASIC1a is involved in fear memory, mood disorders, nociception, and ischemia. Results from single particle analysis at PNCC show the structural role of the highly conserved His-Gly motif within chicken ASIC1a. Citation: "Conserved His-Gly motif of acid-sensing ion channels resides in a reentrant ‘loop’ implicated in gating and ion selectivity" Nate Yoder and Eric Gouaux (2020)