ARCTICA: PNCC'S MAIN SAMPLE SCREENING AND INITIAL DATA COLLECTION PLATFORM
The TFS Talos Arctica is an automated high-throughput transmission electron microscope (TEM) platform focused on single-particle analysis. The constant-power, C-Twin lens delivers outstanding optical performance to allow optimal balance of contrast and resolution. The Arctica is an ideal instrument for screening cryo samples, for exploratory data collection, and for moderately advanced training. It is also a very capable high-resolution data collection instrument, and is capable of achieving single-particle reconstructions of < 3Å.
KRIOS: PNCC’S HIGH-RESOLUTION DATA ACQUISITION PLATFORM
The TFS Titan Krios cryo-transmission electron microscope is a state-of-the-art 300kV instrument optimized for both high-resolution 3D imaging of proteins and macromolecular assemblies, and high-resolution cellular tomography. Its revolutionary design and stability permit a full range of semi-automated applications, including 2D electron crystallography, single-particle analysis, cryo-electron microscopy, and cellular tomography of frozen hydrated samples. The use of 300kV energy, addition of a third condenser lens, and increased optical stability make this the ideal instrument for collecting very large datasets at highest possible resolutions.
GLACIOS 2: PNCC'S SCREENING AND EXPLORATORY DATA COLLECTION PLATFORM
The Thermo Scientific Glacios 2 Cryo-Transmission Electron Microscope (cryo-TEM) is a 200 kV microscope that allows you to easily collect near atomic data from a broad range of biological targets. Compared to the previous generation, the Glacios 2 Cryo-TEM delivers higher throughput and makes cryo-EM more accessible. It features an integrated Thermo Scientific Falcon 4i Direct Electron Detector, Thermo Scientific EPU Software, and a new full enclosure, which combine to enhance image quality, automate data acquisition, and simplify your work. The Glacios 2 Cryo-TEM is ideally suited for single-particle analysis and cryo-electron tomography (cryo-ET).
FALCON 4i: THERMO'S RECENT EM CAMERA
The Thermo Scientific Falcon 4i Direct Electron Detector is the ideal solution for your single particle analysis and cryo-tomography applications. With its unique combination of high image quality, high throughput, efficient lossless data compression enabled via electron-event representation (EER), and a streamlined solution for data management and quality monitoring, the Falcon 4i Detector offers a productivity and performance boost that meets the demands of today’s scientific and industrial communities.
BIOCONTINUUM HD: GATAN'S LATEST ENERGY FILTER
Optimized for cryo-EM and cryo-ET to gain further insight into system function and disease progression at the molecular level.
Selectris/SelectrisX: THERMO'S LATEST ENERGY FILTER
The Thermo Scientific™ Selectris and Selectris X Imaging Filters are post-column imaging filters that improve the contrast of TEM images, resulting in high-resolution structures up to atomic resolution. The zero-loss filtering of the Selectris Filters removes noise caused by inelastically scattered electrons, producing an increased signal-to-noise ratio (SNR) and better contrast. Designed for high stability, the zero-loss peak position of the Selectris Filters is insensitive to temperature variations in the environment, eliminating the need for frequent tuning.
EM GP2: LEICA'S CRYO-TEM SAMPLE PREPARATION
The EM GP2 plunge freezes fluid or extremely thin samples spread on an electron microscopy grid into liquid ethane after removing excess fluid by automatic blotting.
VITROBOT: THERMO'S CRYO-TEM SAMPLE PREPARATION
Vitrobot completely automates the vitrification process to provide fast, easy, reproducible sample preparation - the first step in obtaining high quality images and repeatable experimental results.