Structural results show that different lobes of RSC are responsible for interacting with different structures, including histones, nucleosomal DNA, and nucleosome-Sth1. Citation: "Architecture of the chromatin remodeler RSC and insights into its nucleosome engagement" Avinash B. Patel, Camille M. Moore, Basil J. Greber, Jie Luo, Jeff Ranish and Eva Nogales (2019)